The Champions League group stage has now concluded, with Villarreal sealing the final spot in the last 16 with a 3-2 win at Atalanta.
English teams Manchester City, Liverpool and Manchester United all qualified as seeded teams by topping their respective pools but Chelsea finished second in Group H after conceding a last-minute goal in their final match against Zenit Saint Petersburg.
That means the trio will avoid the likes of Bayern Munich and Real Madrid in the next round but could still end up facing Paris Saint-Germain, Atletico Madrid or Inter Milan, who all progressed as runners-up.
Read on as we detail all the key information ahead of the draw.
When is the Champions League last 16 draw?
The draw for the last 16 will take place at 11am on Monday, December 13, from UEFA’s headquarters in Switzerland.
The draw for the quarter-finals and semi-finals is on Friday, March 18.
How does the last 16 draw work?
The draw features the 16 clubs who advanced by either winning their group or finishing as runner-up. The eight first-placed sides will be seeded and the second-placed teams unseeded.
Group winners will be randomly drawn against one of the unseeded clubs before the pairings face off in a two-legged knockout tie for a place in the quarter-finals, with seeded sides playing at home in the second leg.
Teams who faced each other in the group stage cannot be drawn against each other, nor can sides from the same country.
Which teams are in the Champions League last 16 draw?
Confirmed seeded teams
Ajax, Bayern Munich, Liverpool, Manchester City, Manchester United, Real Madrid, Lille and Juventus all secured a seeded spot in the knockout phase by winning their groups.
Ajax, Bayern, Liverpool, City and United wrapped things up early on, while Real, Juve and Lille needed victories in the final round of fixtures to ensure they finished on top.
Confirmed unseeded teams
PSG, Atletico Madrid, Sporting, Inter, Benfica, FC Salzburg, Chelsea and Villarreal make up a strong unseeded line-up for the last 16.
A dramatic Tuesday night saw Atleti leapfrog Porto and AC Milan into the top two with a 3-1 win over the Portuguese side, while Benfica took advantage of Barcelona’s early exit to seal their place.
When do the last 16 ties take place?
The first legs are scheduled for February 15-16 and 22-23, with the return games pencilled in for March 8-9 and 15-16.
All kick-off times are set for 8pm.
What changes have been made to the last 16 format this season?
UEFA have scrapped the away goals rule for this edition of the competition.
This means ties will go to extra-time if scores are level at the end of 90 minutes, regardless of how many goals either side have scored away from home.
If they are still level after 120 minutes, the tie will be decided by a penalty shootout.
Where and when is the final?
St Petersburg’s Gazprom Arena will host the Champions League final, which is scheduled to take place on Saturday, May 28, 2022.
The venue was initially chosen to host last season’s final but was knocked back a year due to delays caused by the coronavirus pandemic.